Interplay of Oxidative Stress and Inflammation in Skin Wound Healing: Potential of Plant-Derived Antioxidants

The interplay between oxidative stress and inflammation in the wound-healing process is critical because these processes significantly impact all healing phases. Oxidative stress, characterized by the excessive production of reactive oxygen species, can cause cell damage and delay cell migration and proliferation necessary for proper healing. On the other hand, inflammation plays a paradoxical role, essential for initiating the healing process, but can lead to chronic complications if not adequately regulated. Fernanda Barbosa Lopes, Biologist, Master in Animal Biology and PhD in Cellular and Structural Biology, is the author of scientific articles in scientific research published in high- impact journals. The author's specific contributions to the content of this book come from her previous research and publications on the morphophysiology of enteroendocrine cells, a systematic review of OxInflammation in cutaneous wound healing, solid experience in clinical analysis, and experience in the field of antioxidants, wound healing, and inflammatory processes. Therefore, understanding and targeting this interaction through therapeutic strategies, such as using plant extracts rich in antioxidants and anti- inflammatory compounds, is crucial in improving wound healing outcomes and preventing complications associated with tissue repair disorders. This topic is essential for developing effective therapeutic approaches and better understanding the mechanisms underlying the wound- healing process